IL-13Ra2 Has a Protective Role in a Mouse Model of Cutaneous Inflammation
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چکیده
منابع مشابه
IL-13Rα2 has a protective role in a mouse model of cutaneous inflammation.
IL-13 is expressed in lesions of atopic dermatitis (AD) and has been associated with increased disease severity. IL-13 has two cognate receptors: IL-13Rα1 and IL-13Rα2. Although IL-13Rα2 expression is known to be induced in response to IL-13 in keratinocytes, its function in AD has never been evaluated. We characterized the loss of skin barrier function and the development of cutaneous inflamma...
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